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2.5/5 Weak evidence

Recovery evidence brief

Urolithin A

Human trials suggest possible mitochondrial and muscle-endurance effects in older or middle-aged adults, but translation to trained gym users is not established.

Muscle-aging signal endurance / recovery / health 6 linked sources Content audit 2026-05-04

Headline Finding

Older-adult RCTs report mitochondrial and endurance-marker signals; trained-user performance translation is unproven.

Dose Context

Published trials often use 500-1000 mg/day; products are highly specific and not interchangeable with pomegranate intake.

Important Caveat

Longevity, muscle-gain, and endurance guarantees are not supported; most evidence is not in young trained lifters.

Source Drawer

Linked Research

6 papers and evidence links - audit 2026-05-04
  1. Trial Older adults JAMA RCT
  2. Review Older adults PubMed
  3. Trial Middle-aged adults RCT
  4. Trial First-in-human trial
  5. Full text Muscle-aging review full text
  6. Systematic review Mitochondria RCT systematic review

How To Read This Rating

The score reflects evidence that the supplement does its stated job. Some jobs are direct, such as strength, endurance, or recovery; others are indirect, such as sleep, mood, appetite, or health support. A real effect can still receive a cautious practical rating when dose, safety, product quality, or audience fit remain uncertain.

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