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4/5 Strong evidence

Heart health evidence brief

Plant sterols and stanols

Plant sterols and stanols lower LDL cholesterol by reducing cholesterol absorption, but they should be framed as a lipid-marker tool, not a broad heart-health shortcut.

Strong for LDL lowering health 6 linked sources Content audit 2026-05-05

Headline Finding

Dose-response meta-analysis of 124 studies found consistent LDL lowering across roughly 0.6-3.3 g/day intakes.

Dose Context

Common evidence-based intakes are about 1.5-3 g/day with meals, usually from fortified foods or specific capsule/tablet formats.

Important Caveat

They have not replaced outcome-proven therapies. They can lower carotenoid levels slightly, so diet quality still matters.

Source Drawer

Linked Research

6 papers and evidence links - audit 2026-05-05
  1. Meta-analysis RCT meta-analysis full text
  2. Meta-analysis Dose-response meta-analysis
  3. Meta-analysis Sterol vs stanol meta-analysis
  4. Meta-analysis Capsule/tablet meta-analysis
  5. Review EFSA LDL health claim
  6. Meta-analysis Fat-soluble vitamin meta-analysis

How To Read This Rating

The score reflects evidence that the supplement does its stated job. Some jobs are direct, such as strength, endurance, or recovery; others are indirect, such as sleep, mood, appetite, or health support. A real effect can still receive a cautious practical rating when dose, safety, product quality, or audience fit remain uncertain.

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