Back to database
4/5 Strong evidence

Eye health evidence brief

Lutein + zeaxanthin

Lutein and zeaxanthin support macular pigment and have the clearest case in age-related macular degeneration nutrition formulas.

Strong for targeted eye support health / longevity 5 linked sources Content audit 2026-05-05

Headline Finding

AREDS2: adding lutein/zeaxanthin to the formula was safe and secondary analyses favored substitution for beta-carotene in AMD contexts.

Dose Context

AREDS2 used 10 mg lutein plus 2 mg zeaxanthin daily as part of a broader eye-health formula, not as a general vision enhancer.

Important Caveat

The strongest evidence is for people with AMD risk or low dietary intake. It should not be framed as improving normal eyesight in healthy users.

Source Drawer

Linked Research

5 papers and evidence links - audit 2026-05-05
  1. Trial AREDS2 randomized trial
  2. Full text AREDS2 full text
  3. Review NEI AREDS/AREDS2 guidance
  4. Meta-analysis Macular pigment meta-analysis
  5. Review Cochrane AMD antioxidant review

How To Read This Rating

The score reflects evidence that the supplement does its stated job. Some jobs are direct, such as strength, endurance, or recovery; others are indirect, such as sleep, mood, appetite, or health support. A real effect can still receive a cautious practical rating when dose, safety, product quality, or audience fit remain uncertain.

Spot An Evidence Issue?

Send the disputed claim, source link, and why it changes the practical verdict. Corrections that materially affect the claim, dose, caveat, or rating are prioritized.

Report a source or rating issue