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2.5/5 Weak evidence

Sleep / recovery evidence brief

L-ornithine

Small trials suggest fatigue, stress, or sleep effects, but evidence is not strong enough for broad recovery or endurance claims.

Fatigue/sleep signal narrow recovery / endurance / health 6 linked sources Content audit 2026-05-04

Headline Finding

Small RCTs report fatigue or stress/sleep signals; ammonia-clearing performance claims need stronger replication.

Dose Context

Human studies use different hydrochloride or free-form protocols; stress/sleep findings do not automatically generalize to gym output.

Important Caveat

Ammonia-clearing endurance claims need stronger athlete performance data.

Source Drawer

Linked Research

6 papers and evidence links - audit 2026-05-04
  1. Trial Physical fatigue RCT
  2. Trial Stress/sleep RCT full text
  3. Trial Stress/sleep RCT
  4. Trial Exercise/ammonia trial
  5. Trial Mental stress RCT
  6. Review Ornithine-alpha-ketoglutarate review

How To Read This Rating

The score reflects evidence that the supplement does its stated job. Some jobs are direct, such as strength, endurance, or recovery; others are indirect, such as sleep, mood, appetite, or health support. A real effect can still receive a cautious practical rating when dose, safety, product quality, or audience fit remain uncertain.

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